On a general class of conditional tests for family-based association studies in genetics: the asymptotic distribution, the conditional power, and optimality considerations.

Abstract excerpt

Family-based association tests (FBATs) provide simple and powerful tests to detect association between a genetic marker and a disease-susceptibility locus, manifest in subjects by a phenotype or disease trait. Here we propose a new class of conditional tests for family-based association studies that includes most of the established tests and their generalizations. The class of tests is very general; it can be...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Asthma
• Share to Genetic Linkage
• Share to Genotype