Article
Association between physical activity and blood pressure is modified by variants in the G-protein coupled receptor 10.
Hypertension (Dallas, Tex. : 1979) - 1 Feb 2004
Franks Paul W, Bhattacharyya Sumit, Luan Jian'an, Montague Carl, Brennand John, Challis Benjamin, Brage Søren, Ekelund Ulf, Middelberg Rita P S, O'Rahilly Stephen, Wareham Nicholas J
Abstract excerpt
Hypertension is strongly related to cardiovascular disease and all-cause mortality. Exercise reduces blood pressure but the response varies between individuals. The mechanisms by which physical activity energy expenditure (PAEE) modifies blood pressure are not fully defined but include modulation of sympathetic tone. Novel polymorphisms in the G-protein coupled receptor (GPR10) have been linked with high blood...
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