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Article

Peroxisome proliferator-activated receptor-gamma coactivator-1 gene locus: associations with hypertension in middle-aged men.

Hypertension (Dallas, Tex. : 1979) - 1 Feb 2003

Oberkofler Hannes, Hölzl Bertram, Esterbauer Harald, Xie Mingqiang, Iglseder Bernhard, Krempler Franz, Paulweber Bernhard, Patsch Wolfgang

Abstract excerpt

Peroxisome proliferator-activated receptor-gamma coactivator-1 (PPARGC1/PGC-1) is a transcriptional coactivator of nuclear hormone receptors implicated in blood pressure regulation. We therefore ascertained whether the PPARGC1 gene locus is associated with hypertension. We studied associations of 3 polymorphisms in PPARGC1 transcripts with hypertension in 683 middle-aged men and 530 middle-aged women of a...

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Source

Identifiers

PMID: 12574109
DOI: 10.1161/01.hyp.0000050962.48249.b7

Genes

PGC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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