Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of cholecystokinin-A receptor gene polymorphism with alcohol dependence in a Japanese population.

Alcohol and alcoholism (Oxford, Oxfordshire) - 1 Jan 2000

Miyasaka Kyoko, Yoshida Yuki, Matsushita Sachio, Higuchi Susumu, Maruyama Katsuya, Niino Naoakira, Ando Fujiko, Shimokata Hiroshi, Ohta Shigeo, Funakoshi Akihiro

Abstract excerpt

AIMS: Cholecystokinin (CCK), one of the most abundant neurotransmitter peptides, interacts with dopamine. Dopaminergic neurotransmission between the ventral tegmental area and the limbic forebrain is a critical neurobiological component of alcohol and drug self-administration. CCK modulates dopamine release in the nucleus accumbens via the CCK-A receptor (R). We recently determined the transcriptional start site...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcohol-Related Disorders
Share to Aldehyde Dehydrogenase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aldehyde Dehydrogenase, Mitochondrial

Share to Cholecystokinin

Share to Gene Frequency

Share to Polymorphism, Genetic

Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 14691070
DOI: 10.1093/alcalc/agh002

Genes

CCK
ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of cholecystokinin-A receptor gene polymorphism with alcohol dependence in a Japanese population.PMID 14691070Read ↗

Polymorphisms of the CCK, CCKAR and CCKBR genes: an association with alcoholism study.Semantic proximity Read ↗

Association of cholecystokinin-A receptor gene polymorphisms and panic disorder in Japanese.Semantic proximity Read ↗

Investigation of quantitative trait loci in the CCKAR gene with susceptibility to alcoholism.Semantic proximity Read ↗

Association of mu-opioid receptor gene polymorphism A118G with alcohol dependence in a Japanese population.Semantic proximity Read ↗

A new genetic variant in the Sp1 binding cis-element of cholecystokinin gene promoter region and relationship to alcoholism.Semantic proximity Read ↗

Susceptibility locus in neurokinin-1 receptor gene associated with alcohol dependence.Semantic proximity Read ↗

The association of DRD2 -141C and ANKK1 TaqIA polymorphisms with alcohol dependence in Korean population classified by the Lesch typology.Semantic proximity Read ↗

Novel polymorphisms of the human cholecystokinin A receptor gene: an association analysis with schizophrenia.Semantic proximity Read ↗

Polymorphism of the neuropeptide Y gene: an association study with alcohol withdrawal.Semantic proximity Read ↗

Genetic Variability of Incretin Receptors and Alcohol Dependence: A Pilot StudySemantic proximity Read ↗

Genetic association between alcohol withdrawal symptoms and polymorphism of CCK gene promoter.Semantic proximity Read ↗

Gender differences in the genetic risk for alcohol dependence--the results of a pharmacogenetic study in Korean alcoholics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.