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Article

Novel polymorphisms of the human cholecystokinin A receptor gene: an association analysis with schizophrenia.

American journal of medical genetics - 3 Apr 2000

Tachikawa H, Harada S, Kawanishi Y, Okubo T, Shiraishi H

Abstract excerpt

The cholecystokinin A receptor (CCK-AR) modulates CCK-stimulated dopamine release in the posterior nucleus accumbens, and its gene is mapped to 4p15.2-15.1 with the dopamine receptor 5 (DR5) gene. We speculated that alterations in the CCK-AR lead to an increase in dopamine release, which may in turn constitute a predisposition in schizophrenia. We investigated genetic variations in the promoter region and the...

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Source

Identifiers

PMID: 10893485
DOI: 10.1002/(sici)1096-8628(20000403)96:2<141::aid-ajmg3>3.0.co;2-r

Genes

CCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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