Article
Polymorphisms of the CCK, CCKAR and CCKBR genes: an association with alcoholism study.
Journal of studies on alcohol - 1 Jul 2001
Okubo T, Harada S
Abstract excerpt
OBJECTIVE: Cholecystokinin (CCK) plays an important role in the functioning of the central nervous system via an interaction with dopamine and other neurotransmitters. The dopaminergic system has been implicated in the maladaptive behaviors associated with drugs of abuse (e.g., alcohol and cocaine). We analyzed genetic variations in the promoter and coding regions of the CCK, CCKA-receptor (CCKAR) and...
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