Article
Monoglucosyldiacylglycerol, a foreign lipid, can substitute for phosphatidylethanolamine in essential membrane-associated functions in Escherichia coli.
The Journal of biological chemistry - 12 Mar 2004
Wikström Malin, Xie Jun, Bogdanov Mikhail, Mileykovskaya Eugenia, Heacock Philip, Wieslander Ake, Dowhan William
Abstract excerpt
The mechanisms by which lipid bilayer properties govern or influence membrane protein functions are little understood, but a liquid-crystalline state and the presence of anionic and nonbilayer (NB)-prone lipids seem important. An Escherichia coli mutant lacking the major membrane lipid phosphatidylethanolamine (NB-prone) requires divalent cations for viability and cell integrity and is impaired in several...
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