Article
Glycine betaine-assisted protein folding in a lysA mutant of Escherichia coli.
The Journal of biological chemistry - 14 Jan 2000
Bourot S, Sire O, Trautwetter A, Touzé T, Wu L F, Blanco C, Bernard T
Abstract excerpt
Osmoprotectants exogenously supplied to a hyperosmotic culture medium are efficiently imported and amassed by stressed cells of Escherichia coli. In addition to their evident role in the recovery and maintenance of osmotic balance, these solutes should play an important role on the behavior of cellular macromolecules, for example in the process of protein folding. Using a random chemical mutagenesis approach, a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.