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Article

Lipid-engineered Escherichia coli membranes reveal critical lipid headgroup size for protein function.

The Journal of biological chemistry - 9 Jan 2009

Wikström Malin, Kelly Amélie A, Georgiev Alexander, Eriksson Hanna M, Klement Maria Rosén, Bogdanov Mikhail, Dowhan William, Wieslander Ake

Abstract excerpt

Escherichia coli membranes have a substantial bilayer curvature stress due to a large fraction of the nonbilayer-prone lipid phosphatidylethanolamine, and a mutant (AD93) lacking this lipid is severely crippled in several membrane-associated processes. Introduction of four lipid glycosyltransferases from Acholeplasma laidlawii and Arabidopsis thaliana, synthesizing large amounts of two nonbilayer-prone, and two...

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Source

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Identifiers

PMID: 18981182
DOI: 10.1074/jbc.M804482200
PMCID: PMC2613627

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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