Article
The major phospholipid of Escherichia coli, phosphatidylethanolamine, is required for efficient production and secretion of alkaline phosphatase.
Biochemistry. Biokhimiia - 1 Sept 2000
Golovastov V V, Mikhaleva N I, Kadyrova L Y, Nesmeyanova M A
Abstract excerpt
The major phospholipid of the Escherichia coli membranes--the zwitterion phosphatidylethanolamine (PE)--is the only phospholipid involved in the formation of non-bilayer structure of membrane lipids, which is supposed to be necessary for efficient translocation of secreted proteins across the cytoplasmic membrane. The effect of PE on the production and secretion of alkaline phosphatase has been studied in this...
Topics
- Alkaline Phosphatase
- Cardiolipins
- Cations
- Cell Division
- Cell Membrane
- Electrophoresis, Polyacrylamide Gel
- Escherichia coli
- Immunoblotting
- Lipid Bilayers
- Magnesium
- Mutation