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Article

Temperature sensitivity and cell division defects in an Escherichia coli strain with mutations in yghB and yqjA, encoding related and conserved inner membrane proteins.

Journal of bacteriology - 1 Jul 2008

Thompkins Kandi, Chattopadhyay Ballari, Xiao Ying, Henk Margaret C, Doerrler William T

Abstract excerpt

Ludox density gradients were used to enrich for Escherichia coli mutants with conditional growth defects and alterations in membrane composition. A temperature-sensitive mutant named Lud135 was isolated with mutations in two related, nonessential genes: yghB and yqjA. yghB harbors a single missense mutation (G203D) and yqjA contains a nonsense mutation (W92TGA) in Lud135. Both mutations are required for the...

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Identifiers

PMID: 18456815
DOI: 10.1128/JB.00414-08
PMCID: PMC2446817

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