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Article

PKC-dependent phosphorylation may regulate the ability of connexin43 to inhibit DNA synthesis.

Cell communication & adhesion - 1 Jan 2000

Kardami E, Banerji S, Doble B W, Dang X, Fandrich R R, Jin Y, Cattini P A

Abstract excerpt

Phosphorylation affects several biological functions of connexin43 (Cx43), although its role on Cx43-mediated inhibition of DNA synthesis is not known. Previous studies showed increased Cx43 phosphorylation on serine in response to growth factor stimulation of cardiomyocytes, mediated by protein kinase C-epsilon (PKCepsilon). Here we report that activation of PKCepsilon is also necessary for stimulation of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14681031
DOI: 10.1080/cac.10.4-6.293.297

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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