Article
Cardiomyocyte FGF signaling is required for Cx43 phosphorylation and cardiac gap junction maintenance.
Experimental cell research - 15 Aug 2013
Sakurai Takashi, Tsuchida Mariko, Lampe Paul D, Murakami Masahiro
Abstract excerpt
Cardiac remodeling resulting from impairment of myocardial integrity leads to heart failure, through still incompletely understood mechanisms. The fibroblast growth factor (FGF) system has been implicated in tissue maintenance, but its role in the adult heart is not well defined. We hypothesized that the FGF system plays a role in the maintenance of cardiac homeostasis, and the impairment of cardiomyocyte FGF...
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