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Article

Chromosome 18 suppresses prostate cancer metastases.

Urologic oncology - 1 Jan 2000

Padalecki S S, Weldon K S, Reveles X T, Buller C L, Grubbs B, Cui Y, Yin J J, Hall D C, Hummer B T, Weissman B E, Dallas M, Guise T A, Leach R J, Johnson-Pais T L

Abstract excerpt

Loss of heterozygosity and allelic imbalance data has shown that there are two distinct regions of loss on chromosome 18q associated with the progression of prostate cancer (CaP). To investigate the functional significance of chromosome 18q loci in CaP, we utilized the technique of microcell-mediated chromosome transfer to introduce an intact chromosome 18 into the human prostate cancer cell line, PC-3. Three of...

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PMID: 14670546
DOI: 10.1016/s1078-1439(03)00013-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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