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The human Y chromosome suppresses the tumorigenicity of PC‐3, a human prostate cancer cell line, in athymic nude mice

3 Aug 2005

Abstract excerpt

The loss of the Y chromosome is a frequent numerical chromosomal abnormality observed in human prostate cancer. In cancer, loss of specific genetic material frequently accompanies simultaneous inactivation of tumor suppressor genes. It is not known whether the Y chromosome harbors such genes. To address the role of genes on the Y chromosome in human prostate cancer, we transferred a tagged Y chromosome into PC-3,...

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PMID: 16080199
DOI: 10.1002/gcc.20250

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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