Article
Asymmetric interactions between doublesex and tissue- and sex-specific target genes mediate sexual dimorphism in beetles.
Nature communications - 27 Feb 2017
Ledón-Rettig C C, Zattara E E, Moczek A P
Abstract excerpt
Sexual dimorphisms fuel significant intraspecific variation and evolutionary diversification. Yet the developmental-genetic mechanisms underlying sex-specific development remain poorly understood. Here, we focus on the conserved sex-determination gene doublesex (dsx) and the mechanisms by which it mediates sex-specific development in a horned beetle species by combining systemic dsx knockdown, high-throughput...
Topics
- Animals
- Binding Sites
- Coleoptera
- Female
- Gene Expression Profiling
- Gene Expression Regulation, Developmental
- Gene Knockdown Techniques
- Genes, Insect
- Genetic Association Studies
- Insect Proteins
- Male
- Models, Biological
- Organ Specificity
- Phenotype
- RNA Interference
- Sex Characteristics