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Article

Regulation of aldehyde reductase expression by STAF and CHOP.

Genomics - 1 Jan 2004

Barski Oleg A, Papusha Victor Z, Kunkel Gary R, Gabbay Kenneth H

Abstract excerpt

Aldehyde reductase is involved in the reductive detoxification of reactive aldehydes that can modify cellular macromolecules. To analyze the mechanism of basal regulation of aldehyde reductase expression, we cloned the murine gene and adjacent regulatory region and compared it to the human gene. The mouse enzyme exhibits substrate specificity similar to that of the human enzyme, but with a 2-fold higher catalytic...

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PMID: 14667815
DOI: 10.1016/s0888-7543(03)00213-1

Genes

EBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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