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Article

Inhibiting tumor necrosis factor-α signaling attenuates postoperative cognitive dysfunction in aged rats

7 May 2015

Abstract excerpt

Postoperative cognitive dysfunction (POCD), commonly observed in elderly patients, is characterized by impaired concentration, memory and learning following surgery, and may persist for a long duration or progress into serious central nervous system diseases. It has been demonstrated neuroinflammation caused by surgery is involved in the development of POCD. However, the detailed molecular mechanism remains to be...

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PMID: 25955232
DOI: 10.3892/mmr.2015.3744

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