Article
The polymorphisms of the TNF-α gene in multiple sclerosis?--a meta-analysis.
Molecular biology reports - 1 Aug 2011
Xu Lidan, Yuan Weiguang, Sun Haiming, Zhang Xuelong, Jia Xueyuan, Shen Chao, Zhao Yanling, Sun Donglin, Yu Yang, Jin Yan, Fu Songbin
Abstract excerpt
The association between multiple sclerosis (MS) and tumor necrosis factor-alpha gene (TNF-α) polymorphisms has been analyzed in several studies, but conflicting results have been reported. The main purpose of this study was to integrate previous findings and explore whether the three single nucleotide polymorphisms (SNPs; -238G/A, -308G/A, and -376G/A) of TNF-α are associated with susceptibility to MS. A total of...
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