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Article

Impact of CYP2C8 and 2C9 polymorphisms on coronary artery disease and myocardial infarction in the LURIC cohort.

Pharmacogenomics - 1 Oct 2010

Haschke-Becher Elisabeth, Kirchheiner Julia, Trummer Olivia, Grünbacher Gerda, Kainz Alexander, Boehm Bernhard O, März Winfried, Renner Wilfried

Abstract excerpt

AIMS: As data on the cardiovascular risk associated with CYP2C8 and CYP2C9 polymorphisms is controversial, we performed a cross-sectional analysis of subjects enrolled in the Ludwigshafen Risk and Cardiovascular Health (LURIC) study. MATERIALS & METHODS: CYP2C8 and CYP2C9 genetic polymorphisms were determined with real-time PCR in 2827 patients. Based on angiography, 1052 of these patients had coronary artery...

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Identifiers

PMID: 21047199
DOI: 10.2217/pgs.10.96

Genes

CAD

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