Article
CYP2C19 activity and cardiovascular risk factors in patients with an acute coronary syndrome.
Medicina clinica - 20 Sept 2017
Martínez-Quintana Efrén, Rodríguez-González Fayna, Medina-Gil José María, Garay-Sánchez Paloma, Tugores Antonio
Abstract excerpt
INTRODUCTION: CYP2C19 is a major isoform of cytochrome P450 that metabolizes a number of drugs and is involved in the glucocorticoids synthesis. CYP2C19 polymorphisms have been associated with the genetic risk for type 2 diabetes. METHODS: Five hundred and three patients with an acute coronary event were studied to assess the association between the CYP2C19 activity (CYP2C19*2, CYP2C19*3 and CYP2C19*17 variants)...
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