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Article

The risk of myocardial infarction in patients with reduced activity of cytochrome P450 2C9.

Pharmacogenetics and genomics - 1 Jul 2007

Visser Loes E, van Schaik Ron H N, Jan Danser Alexander H, Hofman Albert, Witteman Jacqueline C M, van Duijn Cornelia M, Uitterlinden André G, Pols Huibert A P, Stricker Bruno H Ch

Abstract excerpt

OBJECTIVE: The aim of the present follow-up study was to investigate whether the enzyme activity of the human cytochrome P450 (CYP) 2C9 isoenzyme is associated with myocardial infarction. METHODS: We investigated whether the variant alleles CYP2C9*2 and CYP2C9*3 or the use of CYP2C9 substrates or inhibitors was associated with an increased risk of myocardial infarction in 2210 men and 3534 women from the...

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Identifiers

PMID: 17558303
DOI: 10.1097/01.fpc.0000236335.57046.c8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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