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Article

Mutation of MEF2A in an inherited disorder with features of coronary artery disease.

Science (New York, N.Y.) - 28 Nov 2003

Wang Lejin, Fan Chun, Topol Sarah E, Topol Eric J, Wang Qing

Abstract excerpt

The early genetic pathway(s) triggering the pathogenesis of coronary artery disease (CAD) and myocardial infarction (MI) remain largely unknown. Here, we describe an autosomal dominant form of CAD/MI (adCAD1) that is caused by the deletion of seven amino acids in transcription factor MEF2A. The d...

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Source

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Identifiers

PMID: 14645853
DOI: 10.1126/science.1088477
PMCID: PMC1618876

Genes

CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14645853-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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