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Article

Coronary artery disease and the MEF2A transcription factor.

Science of aging knowledge environment : SAGE KE - 3 Dec 2003

Olson Eric N

Abstract excerpt

Coronary artery disease (CAD) that results from lesions of the vascular wall is a major cause of myocardial infarction (MI) and stroke. A human pedigree with a predisposition to CAD and MI has been shown to harbor a mutation in the MEF2A transcription factor. These findings reveal a new function for this regulator of cardiovascular development and raise intriguing questions about the underlying mechanisms of CAD.

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Source

Identifiers

PMID: 14657507
DOI: 10.1126/sageke.2003.48.pe33

Genes

CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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