Article
Lack of MEF2A mutations in coronary artery disease.
The Journal of clinical investigation - 1 Apr 2005
Weng Li, Kavaslar Nihan, Ustaszewska Anna, Doelle Heather, Schackwitz Wendy, Hébert Sybil, Cohen Jonathan C, McPherson Ruth, Pennacchio Len A
Abstract excerpt
Mutations in MEF2A have been implicated in an autosomal dominant form of coronary artery disease (adCAD1). In this study we sought to determine whether severe mutations in MEF2A might also explain sporadic cases of coronary artery disease (CAD). To do this, we resequenced the coding sequence and splice sites of MEF2A in approximately 300 patients with premature CAD and failed to find causative mutations in the...
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