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Article

Novel 6-bp deletion in MEF2A linked to premature coronary artery disease in a large Chinese family.

Molecular medicine reports - 1 Jul 2016

Xu Dong-Ling, Tian Hong-Liang, Cai Wei-Li, Zheng Jie, Gao Min, Zhang Ming-Xiang, Zheng Zhao-Tong, Lu Qing-Hua

Abstract excerpt

The aim of the present study was to identify the genetic defect responsible for familial coronary artery disease/myocardial infarction (CAD/MI), which exhibited an autosomal dominant pattern of inheritance, in an extended Chinese Han pedigree containing 34 members. Using exome and Sanger sequencing, a novel 6‑base pair (bp) 'CAGCCG' deletion in exon 11 of the myocyte enhancer factor 2A (MEF2A) gene was...

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Identifiers

PMID: 27221044
DOI: 10.3892/mmr.2016.5297
PMCID: PMC4918543

Genes

CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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