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Article

Phosphatidylserine receptor is required for clearance of apoptotic cells.

Science (New York, N.Y.) - 28 Nov 2003

Li Ming O, Sarkisian Matthew R, Mehal Wajahat Z, Rakic Pasko, Flavell Richard A

Abstract excerpt

Cells undergoing apoptosis during development are removed by phagocytes, but the underlying mechanisms of this process are not fully understood. Phagocytes lacking the phosphatidylserine receptor (PSR) were defective in removing apoptotic cells. Consequently, in PSR-deficient mice, dead cells accumulated in the lung and brain, causing abnormal development and leading to neonatal lethality. A fraction of PSR...

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Identifiers

PMID: 14645847
DOI: 10.1126/science.1087621

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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