Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Context-dependent compensation among phosphatidylserine-recognition receptors

1 Nov 2017

Abstract excerpt

Abstract Phagocytes express multiple phosphatidylserine (PtdSer) receptors that recognize apoptotic cells. It is unknown whether these receptors are interchangeable or if they play unique roles during cell clearance. Loss of the PtdSer receptorMertkis associated with apoptotic corpse accumulation in the testes and degeneration of photoreceptors in the eye. Both phenotypes are linked to impaired phagocytosis by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell death mechanisms and regulation
Share to Erythrocyte Function and Pathophysiology
Share to Phagocytosis and Immune Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29116131
DOI: 10.1038/s41598-017-15191-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Context-dependent compensation among phosphatidylserine-recognition receptorsPMID 29116131Read ↗

Distinct mouse models of Stargardt disease display differences in pharmacological targeting of ceramides and inflammatory responsesSemantic proximity Read ↗

TAM receptors in phagocytosis: Beyond the mere internalization of particlesSemantic proximity Read ↗

MERTK-Mediated LC3-Associated Phagocytosis (LAP) of Apoptotic Substrates in Blood-Separated Tissues: Retina, Testis, Ovarian FolliclesSemantic proximity Read ↗

Abca4, mutated in Stargardt disease, is required for structural integrity of cone outer segments.Semantic proximity Read ↗

Optineurin tunes outside-in signaling to regulate lysosome biogenesis and phagocytic clearance in the retinaSemantic proximity Read ↗

TAM receptors in apoptotic cell clearance, autoimmunity, and cancerSemantic proximity Read ↗

The retromer complex is required for rhodopsin recycling and its loss leads to photoreceptor degeneration.Semantic proximity Read ↗

Tissue-specific modifier alleles determine <i>Mertk</i> loss-of-function traitsSemantic proximity Read ↗

MERTK-Dependent Ensheathment of Photoreceptor Outer Segments by Human Pluripotent Stem Cell-Derived Retinal Pigment Epithelium.Semantic proximity Read ↗

Tissue-specific modifier alleles determine Mertk loss-of-function traits.Semantic proximity Read ↗

A lysosomal tetraspanin associated with retinal degeneration identified via a genome-wide screen.Semantic proximity Read ↗

Pretaporter, a Drosophila protein serving as a ligand for Draper in the phagocytosis of apoptotic cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.