Article
Phosphatidylserine receptor is required for the engulfment of dead apoptotic cells and for normal embryonic development in zebrafish.
Development (Cambridge, England) - 1 Nov 2004
Hong Jiann-Ruey, Lin Gen-Hwa, Lin Cliff Ji-Fan, Wang Wan-Ping, Lee Chien-Chung, Lin Tai-Lang, Wu Jen-Leih
Abstract excerpt
During development, the role of the phosphatidylserine receptor (PSR) in the removal of apoptotic cells that have died is poorly understood. We have investigated this role of PSR in developing zebrafish. Programmed cell death began during the shield stage, with dead cells being engulfed by a neighboring cell that showed a normal-looking nucleus and the nuclear condensation multi-micronuclei of an apoptotic cell....
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