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Article

Three Drosophila EXT genes shape morphogen gradients through synthesis of heparan sulfate proteoglycans.

Development (Cambridge, England) - 1 Jan 2004

Takei Yuki, Ozawa Yutakahiko, Sato Makoto, Watanabe Akira, Tabata Tetsuya

Abstract excerpt

The signaling molecules Hedgehog (Hh), Decapentaplegic (Dpp) and Wingless (Wg) function as morphogens and organize wing patterning in Drosophila. In the screen for mutations that alter the morphogen activity, we identified novel mutants of two Drosophila genes, sister of tout-velu (sotv) and brot...

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Identifiers

PMID: 14645127
DOI: 10.1242/dev.00913

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14645127-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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Three Drosophila EXT genes shape morphogen gradients through synthesis of heparan sulfate proteoglycans.PMID 14645127Read ↗

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