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Article

A possible association between an insertion/deletion polymorphism of the NQO2 gene and schizophrenia.

Psychiatric genetics - 1 Dec 2003

Harada Shoji, Tachikawa Hirokazu, Kawanishi Yoichi

Abstract excerpt

OBJECTIVE: Glutathione-S-transferases, NAD(P)H: quinone oxidoreductase1 (NQO1) and NRH: quinone oxidoreductase2 (NQO2) provide important cellular defences against the neurotoxicity induced by catecholamine-derived o-quinones and oxidative stress during redox cycling. In this study, we investigated the association between polymorphisms of the NQO2 gene and schizophrenia. METHODS: We analysed the promoter and...

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Topics

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Share to Base Sequence
Share to Genetic Variation
Share to Mutagenesis, Insertional

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymerase Chain Reaction

Share to Polymorphism, Single-Stranded Conformational

Share to Quinone Reductases

Share to Schizophrenia

Share to Sequence Deletion

Source

Identifiers

PMID: 14639047
DOI: 10.1097/00041444-200312000-00003

Genes

NQO2
NQO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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