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Article

Sp3 repression of polymorphic human NRH:quinone oxidoreductase 2 gene promoter.

Free radical biology & medicine - 15 Oct 2004

Wang Wei, Jaiswal Anil K

Abstract excerpt

Human NRH:quinone oxidoreductase 2 (NQO2) gene-containing 29-bp deletion/insertion polymorphic promoters were found to be associated with susceptibility to Parkinson's disease. Here, we demonstrate that the NQO2 gene is differentially expressed by the polymorphic promoters in human fibroblasts and Hep-G2 cells transfected with NQO2 gene reporter constructs. Promoter containing the 29-bp insertion polymorphism...

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Source

Identifiers

PMID: 15451063
DOI: 10.1016/j.freeradbiomed.2004.06.042

Genes

NQO2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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