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Article

Association analyses between polymorphisms of the phase II detoxification enzymes (GSTM1, NQO1, NQO2) and alcohol withdrawal symptoms.

Alcoholism, clinical and experimental research - 1 Aug 2003

Okubo Takehito, Harada Shoji, Higuchi Susumu, Matsushita Sachio

Abstract excerpt

BACKGROUND: NRH-quinone oxidoreductase 2 (NQO2) along with glutathione S-transferase M1 (GSTM1) and NAD(P)H-quinone oxidoreductase 1 (NQO1), which is involved in phase II detoxification reactions, is thought to be important for detoxification of catechol o-quinones in the central nervous system. Our previous study revealed that the human NQO2 gene is highly polymorphic. In this study, we investigated a possible...

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Share to NAD(P)H Dehydrogenase (Quinone)

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Source

Identifiers

PMID: 12960511
DOI: 10.1097/01.ALC.0000078616.63296.41

Genes

NQO2
GSTM1
NQO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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