Article
[Interluekin-1 beta genetic polymorphism influences the impact of cytochrome P 2C19 genotype on the cure rate of H. pylori eradication therapy].
Nihon rinsho. Japanese journal of clinical medicine - 1 Mar 2004
Mizuno Motowo, Take Susumu, Ishiki Kuniharu, Okada Hiroyuki, Shiratori Yasushi
Abstract excerpt
Genetic polymorphism of interleukin(IL)-1 beta is associated with differences in gastric acid suppression in response to H. pylori infection. Thus, the polymorphism might affect H. pylori eradication therapy since antibiotics used in treatment regimens may be acid-sensitive. We examined the impact of IL-1 beta genetic polymorphism on the cure rate of triple therapy for H. pylori in relation to cytochrome...
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