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Article

Time sequence of maturation of dystrophic neurites associated with Abeta deposits in APP/PS1 transgenic mice.

Experimental neurology - 1 Nov 2003

Blanchard Véronique, Moussaoui Saliha, Czech Christian, Touchet Nathalie, Bonici Bruno, Planche Michel, Canton Thierry, Jedidi Iness, Gohin Micheline, Wirths Oliver, Bayer Thomas A, Langui Dominique, Duyckaerts Charles, Tremp Günter, Pradier Laurent

Abstract excerpt

Several novel transgenic mouse models expressing different mutant APPs in combination with mutant PS1 have been developed. These models have been analyzed to investigate the formation and progressive alterations of dystrophic neurites (DNs) in relation to Abeta deposits. In the most aggressive model, Abeta deposits appear as early as 2.5 months of age. Maturation of DNs was qualitatively quite similar among...

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Share to Amyloid beta-Protein Precursor
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PMID: 14637096
DOI: 10.1016/s0014-4886(03)00252-8

Genes

APP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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