Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Early onset amyloid lesions lead to severe neuritic abnormalities and local, but not global neuron loss in APPPS1 transgenic mice

23 Oct 2010

Abstract excerpt

No abstract is available from the source.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Prion Diseases and Protein Misfolding
Share to Trace Elements in Health

Source

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Identifiers

PMID: 20970889
DOI: 10.1016/j.neurobiolaging.2010.08.014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 20 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Early onset amyloid lesions lead to severe neuritic abnormalities and local, but not global neuron loss in APPPS1 transgenic micePMID 20970889Read ↗

Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formationSemantic proximity Read ↗

Aβ42‐driven cerebral amyloidosis in transgenic mice reveals early and robust pathologySemantic proximity Read ↗

Characterization of amyloid deposition in the APPswe/PS1dE9 mouse model of Alzheimer diseaseSemantic proximity Read ↗

Neurofilament light gene deletion exacerbates amyloid, dystrophic neurite, and synaptic pathology in the APP/PS1 transgenic model of Alzheimer's diseaseSemantic proximity Read ↗

Neuroanatomical Abnormalities in Behaviorally Characterized APPV717F Transgenic MiceSemantic proximity Read ↗

Neuron loss in APP transgenic miceSemantic proximity Read ↗

Clinical features of early-onset Alzheimer disease in a large kindred with an E280A presenilin-1 mutationSemantic proximity Read ↗

BACE1 gene deletion prevents neuron loss and memory deficits in 5XFAD APP/PS1 transgenic miceSemantic proximity Read ↗

Brain Abeta amyloidosis in APPsw mice induces accumulation of presenilin-1 and tau.Semantic proximity Read ↗

Amyloid generation and dysfunctional immunoproteasome activation with disease progression in animal model of familial Alzheimer's disease.Semantic proximity Read ↗

APPSW Transgenic Mice Develop Age-related Aβ Deposits and Neuropil Abnormalities, but no Neuronal Loss in CA1Semantic proximity Read ↗

Early intraneuronal accumulation and increased aggregation of phosphorylated Abeta in a mouse model of Alzheimer’s diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.