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Article

Overlap of nuclear localisation signal and specific DNA-binding residues within the zinc finger domain of PacC.

Journal of molecular biology - 5 Dec 2003

Fernández-Martínez Javier, Brown Christopher V, Díez Eliecer, Tilburn Joan, Arst Herbert N, Peñalva Miguel A, Espeso Eduardo A

Abstract excerpt

The transcription factor PacC, mediating regulation of gene expression by ambient pH in the genetically amenable fungus Aspergillus nidulans, contains a three zinc finger DNA-binding domain (zf-DBD) including a nuclear localisation signal (NLS). We selected 38 novel mutations impairing PacC function, of which 21 missense mutations identify individual residues essential for zf-DBD structure/function. Our...

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Identifiers

PMID: 14636595
DOI: 10.1016/j.jmb.2003.09.072

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Overlap of nuclear localisation signal and specific DNA-binding residues within the zinc finger domain of PacC.PMID 14636595Read ↗

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