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Article

Identification, cloning and analysis of the Aspergillus niger gene pacC, a wide domain regulatory gene responsive to ambient pH.

Molecular & general genetics : MGG - 25 Feb 1996

MacCabe A P, Van den Hombergh J P, Tilburn J, Arst H N, Visser J

Abstract excerpt

A wide domain regulatory gene implicated in modulating gene expression in response to ambient pH has been cloned and sequenced from the industrially useful filamentous fungus Aspergillus niger. This gene, pacC, is able to restore a pacC+ phenotype to A. nidulans pacCc11 and pacCc14 mutants with respect to extent of conidiation, conidial pigment intensity and acid phosphatase regulation. The pacC gene of A. niger...

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PMID: 8602152
DOI: 10.1007/BF02174395

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification, cloning and analysis of the Aspergillus niger gene pacC, a wide domain regulatory gene responsive to ambient pH.PMID 8602152Read ↗

Refining the pH response in Aspergillus nidulans: a modulatory triad involving PacX, a novel zinc binuclear cluster protein.Semantic proximity Read ↗

Activation of the Aspergillus PacC transcription factor in response to alkaline ambient pH requires proteolysis of the carboxy-terminal moiety.Semantic proximity Read ↗

Transcription of Aspergillus nidulans pacC is modulated by alternative RNA splicing of palB.Semantic proximity Read ↗

The pH signalling transcription factor PacC controls virulence in the plant pathogen Fusarium oxysporum.Semantic proximity Read ↗

Signaling of ambient pH in Aspergillus involves a cysteine protease.Semantic proximity Read ↗

Biosynthesis and uptake of siderophores is controlled by the PacC-mediated ambient-pH Regulatory system in Aspergillus nidulans.Semantic proximity Read ↗

Molecular and cellular analysis of the pH response transcription factor PacC in the fungal symbiont Epichloë festucae.Semantic proximity Read ↗

pH-Signaling Transcription Factor AopacC Regulates Ochratoxin A Biosynthesis in Aspergillus ochraceus.Semantic proximity Read ↗

The pH-induced glycosylation of secreted phosphatases is mediated in Aspergillus nidulans by the regulatory gene pacC-dependent pathway.Semantic proximity Read ↗

Adaptation to pH and Role of PacC in the Rice Blast Fungus Magnaporthe oryzaeSemantic proximity Read ↗

The Aspergillus pH-responsive transcription factor PacC regulates virulence.Semantic proximity Read ↗

Phenotypic characterization of mutants of the citrus pathogen Colletotrichum acutatum defective in a PacC-mediated pH regulatory pathway.Semantic proximity Read ↗

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