Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutational analysis of the pH signal transduction component PalC of Aspergillus nidulans supports distant similarity to BRO1 domain family members.

Genetics - 1 Sept 2005

Tilburn Joan, Sánchez-Ferrero Juan C, Reoyo Elena, Arst Herbert N, Peñalva Miguel A

Abstract excerpt

The alkaline ambient pH signal transduction pathway component PalC has no assigned molecular role. Therefore we attempted a gene-specific mutational analysis and obtained 55 new palC loss-of-function alleles including 24 single residue substitutions. Refined similarity searches reveal conserved PalC regions including one with convincing similarity to the BRO1 domain, denoted PCBROH, where clustering of mutational...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aspergillus nidulans
Share to Conserved Sequence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endosomal Sorting Complexes Required for Transport

Share to Fungal Proteins

Share to Hydrogen-Ion Concentration

Share to Saccharomyces cerevisiae Proteins

Share to Sequence Homology, Amino Acid

Share to Vesicular Transport Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 15944343
DOI: 10.1534/genetics.105.044644
PMCID: PMC1456523

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutational analysis of the pH signal transduction component PalC of Aspergillus nidulans supports distant similarity to BRO1 domain family members.PMID 15944343Read ↗

Establishment of the ambient pH signaling complex in Aspergillus nidulans: PalI assists plasma membrane localization of PalH.Semantic proximity Read ↗

Physiological involvement in pH signaling of Vps24-mediated recruitment of Aspergillus PalB cysteine protease to ESCRT-III.Semantic proximity Read ↗

Putative membrane components of signal transduction pathways for ambient pH regulation in Aspergillus and meiosis in saccharomyces are homologous.Semantic proximity Read ↗

Ambient pH signalling in ascomycetous yeasts involves homologues of the Aspergillus nidulans genes palF and paIH.Semantic proximity Read ↗

pH Response Pathways in Fungi: Adapting to Host-derived and Environmental SignalsSemantic proximity Read ↗

pH regulation in Aspergillus and parallels with higher eukaryotic regulatory systems.Semantic proximity Read ↗

Activation of the Aspergillus PacC transcription factor in response to alkaline ambient pH requires proteolysis of the carboxy-terminal moiety.Semantic proximity Read ↗

Characterization of additional components of the environmental pH-sensing complex in the pathogenic fungus Cryptococcus neoformans.Semantic proximity Read ↗

Deletions of endocytic components VPS28 and VPS32 affect growth at alkaline pH and virulence through both RIM101-dependent and RIM101-independent pathways in Candida albicans.Semantic proximity Read ↗

Ambient pH signalling in the yeast Yarrowia lipolytica involves YlRim23p/PalC, which interacts with Snf7p/Vps32p, but does not require the long C terminus of YlRim9p/PalI.Semantic proximity Read ↗

Malassezia responds to environmental pH signals through the conserved Rim/Pal pathwaySemantic proximity Read ↗

Two new genes involved in signalling ambient pH in Aspergillus nidulans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.