Article
Refining the pH response in Aspergillus nidulans: a modulatory triad involving PacX, a novel zinc binuclear cluster protein.
Molecular microbiology - 1 Dec 2015
Bussink Henk-Jan, Bignell Elaine M, Múnera-Huertas Tatiana, Lucena-Agell Daniel, Scazzocchio Claudio, Espeso Eduardo A, Bertuzzi Margherita, Rudnicka Joanna, Negrete-Urtasun Susana, Peñas-Parilla Maria M, Rainbow Lynne, Peñalva Miguel Á, Arst Herbert N, Tilburn Joan
Abstract excerpt
The Aspergillus nidulans PacC transcription factor mediates gene regulation in response to alkaline ambient pH which, signalled by the Pal pathway, results in the processing of PacC(72) to PacC(27) via PacC(53). Here we investigate two levels at which the pH regulatory system is transcriptionally moderated by pH and identify and characterise a new component of the pH regulatory machinery, PacX. Transcript level...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.