Article
Strategies for mapping and identifying quantitative trait loci specifying behavioral responses to alcohol.
Alcoholism, clinical and experimental research - 1 Aug 1995
Buck K J
Abstract excerpt
Most responses to alcohol in both humans and animals are heritable, and this genetic sensitivity to ethanol is determined by multiple genes. However, the number of genes, their identities, and just how they determine susceptibility to the actions of alcohol are unknown. Herein, we describe a multistage strategy for mapping quantitative trait loci (QTLs) using recombinant inbred strains and F2 mice. Precise...
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