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Article

Receptor interactions involved in adenoviral-mediated gene delivery after systemic administration in non-human primates.

Human gene therapy - 20 Nov 2003

Smith Theodore A G, Idamakanti Neeraja, Marshall-Neff Jennifer, Rollence Michele L, Wright Patrick, Kaloss Michele, King Laura, Mech Christine, Dinges Lisa, Iverson William O, Sherer Alfred D, Markovits Judit E, Lyons Russette M, Kaleko Michael, Stevenson Susan C

Abstract excerpt

Adenovirus serotype 5 (Ad5)-based vectors can bind at least three separate cell surface receptors for efficient cell entry: the coxsackie-adenovirus receptor (CAR), alpha nu integrins, and heparan sulfate glycosaminoglycans (HSG). To address the role of each receptor involved in adenoviral cell e...

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PMID: 14633402
DOI: 10.1089/104303403322542248

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-14633402-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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