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Article

Capsid modification strategies for detargeting adenoviral vectors.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2014

Parker Alan L, Bradshaw Angela C, Alba Raul, Nicklin Stuart A, Baker Andrew H

Abstract excerpt

Adenoviral vectors hold immense potential for a wide variety of gene therapy based applications; however, their efficacy and toxicity is dictated by "off target" interactions that preclude cell specific targeting to sites of disease. A number of "off target" interactions have been described in the literature that occur between the three major capsid proteins (hexon, penton, and fiber) and components of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24132476
DOI: 10.1007/978-1-62703-679-5_3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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