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Article

An Immunodominant Epitope of Myelin Basic Protein Is an Amphipathic α-Helix

1 Feb 2004

Abstract excerpt

Myelin basic protein is a candidate autoantigen in multiple sclerosis. One of its dominant antigenic epitopes is segment Pro85 to Pro96 (human sequence numbering, corresponding to Pro82 to Pro93 in the mouse). There have been several, contradictory predictions of secondary structure in this region; either beta-sheet, alpha-helix, random coil, or combinations thereof have all been proposed. In this paper,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 14630913
DOI: 10.1074/jbc.m311504200

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