Article
Major Myelin proteolipid: the 4-alpha-helix topology.
The Journal of membrane biology - 1 Mar 1991
Popot J L, Pham Dinh D, Dautigny A
Abstract excerpt
Several conflicting models have been proposed for the membrane arrangement of the major myelin proteolipid (PLP). We have compared features of the sequence of PLP with those of other eukaryotic integral membrane proteins, with the view of identifying the most likely transmembrane topology. A new,...
Topics
- Amino Acid Sequence
- Animals
- Cell Membrane
- Diffuse Cerebral Sclerosis of Schilder
- Disulfides
- Dogs
- Endopeptidases
- Immunohistochemistry
- Mice
- Models, Molecular
- Molecular Sequence Data
- Mutation
- Myelin Proteins
- Myelin Proteolipid Protein
- Myelin Sheath
- Oligodendroglia
- Protein Conformation
- X-Ray Diffraction