Article
A rapid and simple CYP2D6 genotyping assay--case study with the analgetic tramadol.
Metabolism: clinical and experimental - 1 Nov 2003
Borlak Jürgen, Hermann Robert, Erb Katharina, Thum Thomas
Abstract excerpt
There is substantial evidence for a causal relationship between genetic variability of the CYP2D6 gene and changes in the pharmacokinetics of drugs. Therefore, knowledge of single-nucleotide polymorphisms (SNPs) prior to drug administration is highly desired for assisting in the development of in...
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