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Article

Additive effects of PDGF receptor beta signaling pathways in vascular smooth muscle cell development.

PLoS biology - 1 Nov 2003

Tallquist Michelle D, French Wendy J, Soriano Philippe

Abstract excerpt

The platelet-derived growth factor beta receptor (PDGFRbeta) is known to activate many molecules involved in signal transduction and has been a paradigm for receptor tyrosine kinase signaling for many years. We have sought to determine the role of individual signaling components downstream of this receptor in vivo by analyzing an allelic series of tyrosine-phenylalanine mutations that prevent binding of specific...

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Share to Muscle, Smooth, Vascular
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptor, Platelet-Derived Growth Factor beta

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Source

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Identifiers

PMID: 14624252
DOI: 10.1371/journal.pbio.0000052
PMCID: PMC261889

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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