Article
Inducible nitric oxide synthase promoter polymorphism in human brucellosis.
Microbes and infection - 1 Nov 2003
Orozco Gisela, Sánchez Elena, López-Nevot Miguel Angel, Caballero Abelardo, Bravo María José, Morata Pilar, de Dios Colmenero Juan, Alonso Antonio, Martín Javier
Abstract excerpt
Nitric oxide (NO), produced by the inducible nitric oxide synthase (NOS2) protein, is a defence mechanism against various pathogens, including bacteria of the genus Brucella. The aim of this study was to investigate the possible association between the NOS2 gene promoter polymorphism, TAAA(n) and CCTTT(n) microsatellites, and the predisposition to human brucellosis. We performed a case-control study in 85...
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