Article
Genetic determinants of rheumatoid arthritis: the inducible nitric oxide synthase (NOS2) gene promoter polymorphism.
Genes and immunity - 1 Aug 2002
Pascual M, López-Nevot M A, Cáliz R, Koeleman B P C, Balsa A, Pascual-Salcedo D, Martín J
Abstract excerpt
An association study and a linkage analysis were carried out in parallel in order to investigate the association of the inducible nitric oxide synthase (NOS2) gene promoter polymorphism with rheumatoid arthritis (RA) predisposition and/or outcome including a -954G-C mutation, a di-allelic (TAAA)(n) marker and the highly polymorphic (CCTTT). The -954G-C point mutation occurred non-polymorphic and the di-allelic...
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