Article
Association of a functional inducible nitric oxide synthase promoter variant with susceptibility to biopsy-proven giant cell arteritis.
The Journal of rheumatology - 1 Nov 2005
Gonzalez-Gay Miguel A, Oliver Javier, Sanchez Elena, Garcia-Porrua Carlos, Paco Laura, Lopez-Nevot Miguel A, Ollier William E R, Martin Javier
Abstract excerpt
OBJECTIVE: To assess the contribution of 2 polymorphisms within the inducible nitric oxide (NOS2A) promoter region to susceptibility to giant cell arteritis (GCA). METHODS: One hundred three patients with biopsy-proven GCA and 198 ethnically matched controls from the Lugo region (Northwest Spain) were studied. Patients and controls were genotyped using polymerase chain reaction techniques for a multiallelic...
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